Additional slots for artifacts can be added at Skadovsk by a technician or at Yanov by using modifications that require tools for fine work and calibration. The number of simultaneously used artifacts in a suit is limited by special cells. For example, the negative effect of two Goldfish (radiation +6) is overridden by the positive properties of two Bubbles (radiation -8) and there is still room for the Eye (radiation +2). Therefore, it is necessary to select artifacts in such a way that the resulting negative effect is smoothed out and does not cause damage to health. Most often it is negative, since radiation negatively affects the body of the protagonist. The impact can be both positive and negative. Each anomaly gives rise to a family of two or three artifacts of a similar type, which differ in appearance and strength of impact on the host's body. : Call of Pripyat are generated by thermal, chemical, electrical, radiation, organic and gravitational anomalies. The location of old artifacts in anomalies changes. Emissions in the Zone occur once or twice a day. Artifacts are mysterious formations with unique properties that appear in places of anomalies after emissions.
: Call of Pripyat' is unlocked after finding 23 artifacts.
The achievement 'Seeker' (English Artifact Hunter) in 'S.T.A.L.K.E.R.